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The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases

Career Opportunities

CENTRE FOR STEM CELL RESEARCH

The newly established Centre for Stem Cell Research (CSCR) invites applications for Faculty, Post Doctoral and Graduate Student positions. Faculty recruits will be expected to develop a competitive research program focused on fundamental stem cell biology and/or clinical translation of stem cell research.

The CSCR is housed in the Brown Foundation Institute of Molecular Medicine (IMM). The IMM is located in the heart of the Texas Medical Center, the largest medical center in the world which provides an outstanding environment for research and clinical/translational studies.

Current research focuses of the CSCR include:

  • Molecular dissection of hematopoietic stem cell niches
  • Fundamental properties and therapeutic applications of mesenchymal stem cells
  • Correcting genetic diseases by genome editing in stem cells
  • Investigating the link between obesity and cancer
  • Tumor-initiating cells in hematological malignancies
  • Controlled differentiation of ES cells
  • Applications in all areas of stem cell research are encouraged.

    The Centre for Stem Cell Research has access to outstanding core facilities including flow cytometry, microscopy, ES cell culture, proteomics and a state-of-the-art barrier vivarium.

    Prospective candidates should send their CV to:

    Dr. Paul J. Simmons, Professor and Director, Centre for Stem Cell Research
    C/O: Dr. Jeannie Ann Javni, Research Manager, Centre for Stem Cell Research
    Brown Foundation Institute of Molecular Medicine
    1825 Pressler Street, Houston, TX 77030

    For more information on this position, please visit our Human Resources website.

    The University of Texas is an EO/AA employer. M/F/D/V.  This is a security-sensitive position and thereby subject to Texas Education Code §51.215. A background check will be required for the final candidate.


    CENTER FOR CARDIOVASCULAR GENETICS

    Cardiovascular Genetics Faculty

    The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases (IMM) at the University of Texas Health Science Center at Houston under the leadership of Dr. C. Thomas Caskey is recruiting faculty in cardiovascular genetics. Both Ph.D. and M.D.-Ph.D. applicants who have established records of independent and innovative research are encouraged to apply. Genomic structural variations and epigenetics are high priority areas. The appointments provide programmatic support enabling rapid establishment of independent research initiatives. 

    The IMM is located in new state-of-the-art research facilities (230,000 square feet), which has been honored with seven awards for architectural design. The focus of the Institute is discovery of major genetic and molecular mechanisms of disease toward the objective of preventing disease.

    Please email a description of your program and a copy of your curriculum vitae to: Sarah.Cuddy@uth.tmc.edu

    The University of Texas is an EO/AA employer. M/F/D/V.  This is a security-sensitive position and thereby subject to Texas Education Code §51.215. A background check will be required for the final candidate.

    Bioinformatics Scientific Programmer

    Make a difference at the cutting edge of biomedical research.  The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases (IMM), at The University of Texas Health Science Center at Houston, is studying and preventing diseases at the genetic, cellular and molecular levels using state-of-the-art genomic and proteomic technologies, animal models and clinical studies.

    The IMM is seeking a motivated bioinformatics programmer to lead data analysis and data integration for research projects involving vast amounts of sequencing data produced by next-generation sequencing technologies (predominantly from the Illumina platform).  Applications include medical resequencing involving identification of genetic variants involved in cardiovascular and stroke risk, transcriptome analysis and CHIP-seq. The successful candidate must be independent, driven and organized, being able to manage their time over several projects concurrently. Analysis is expected to involve pipeline development, custom programming and integration of third party tools. The candidate will be expected to work closely with biomedical research teams to design innovative experimental strategies, prepare detailed software and database specifications, design, code, test, debug, document and maintain programs.  The candidate will be expected to assist in the preparation of data for grants, publications and academic presentations and will have the opportunity to publish work as appropriate.

    Requirements:

    • M.S. or Ph.D. degree in Computing, Bioinformatics or a related biological science field.
    • Programming experience in Perl, Java, Unix/Linux shell scripting.
    • Experience working with relational databases and schema design.
    • 3-5 years experience in bioinformatics and genomic analysis.
    • Ability to work both independently and in a team environment.
    • Excellent communication skills.

    Interested individuals should submit a CV and three references to the attention of:

    Simon H. Sims, Ph.D.
    THI at St. Luke’s Episcopal Hospital
    The Institute of Molecular Medicine (IMM), Cardiovascular Genetics, DAC-900
    6770 Bertner Ave,
    Houston, TX 77030

    For more information on this position, please visit our Human Resources website.

    The University of Texas is an EO/AA employer. M/F/D/V.  This is a security-sensitive position and thereby subject to Texas Education Code §51.215. A background check will be required for the final candidate.


    Research Assistant II

    The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases (IMM) at the University of Texas Health Science Center at Houston is currently accepting applications for a Research Assistant II in the Research Biological Sciences under the direction of Dr. Simon Sims

    Applications objectives are to identify sequence variants that may be associated with disease by screening 100s of clinical samples.  Other key accountabilities include, but are not limited to the following:

    • Conduct molecular biology research activities including PCR, qPCR, nucleic acid purification and hybridization

    • Conduct sample preparation for deep-resequencing, expression analysis and other genomic applications

    • Operate a next-generation DNA sequencing instrument

    • Manage the day-to-day lab duties, including purchasing lab supplies and routine lab equipment maintenance

    • Trouble shoot laboratory and experimental problems

    • Exerts up to 20 pounds of force occasionally and/or up to 10 pounds and or a negligible amount constantly to move objects

    Working under the faculty investigator:

    • Participate in DNA sequence data analysis, as needed

    • Maintain accurate and timely records including notebooks and databases, as needed by ongoing research projects.

    Education and Qualifications:

    • Depending on project(s), Certification for Protection of Human Research Subjects may be required

    • Bachelor degree in a biological science or relevant experience in lieu of education.

    • Minimum of 1 year of related experience in a research laboratory environment

    Interested individuals should submit a CV and three references to the attention of:

    Simon H. Sims, Ph.D.
    THI at St. Luke's Episcopal Hospital
    The Institute of Molecular Medicine (IMM), Cardiovascular Genetics, DAC-900
    6770 Bertner Ave,
    Houston, TX 77030

    Please visit our Human Resources website to apply and for more information on this position.

    The University of Texas is an EO/AA employer. M/F/D/V.  This is a security-sensitive position and thereby subject to Texas Education Code §51.215. A background check will be required for the final candidate.


    Immunology Faculty

    Research Center for Immunology and Autoimmune Diseases, is currently expanding and invites applications for faculty positions at the Assistant Professor level, although candidates at the Associate Professor rank may also be considered.   We are particularly interested in recruiting in the areas of mucosal immunology and immune tolerance; however, inquires by outstanding candidates in other areas of immunology/inflammation are encouraged. The appointment will provide substantial start-up support.  On-site core facilities available at  our new state-of-the-art research building (230,000 square feet) include a barrier vivarium, transgenic mouse services, confocal microscopy, flow cytometry and cell sorting, high-throughput DNA sequencing, and mass spectroscopy. Cross appointments in basic science and/or clinical departments of The University of Texas Health Science Center at Houston will be arranged as appropriate. Collaborations are available and encouraged with other faculty members both at the IMM (faculty and programs can be reviewed online) and within the Texas Medical Center.

    Interested applicants should send their curriculum vita and research program description to the attention of:

    Rick A. Wetsel, PhD
    Research Center for Immunology and Autoimmune Diseases
    The Brown Foundation Institute of Molecular Medicine
    The University of Texas Health Science Center at Houston
    1825 Pressler Street, Suite 205
    Rick.A.Wetsel@uth.tmc.edu

    The University of Texas is an EO/AA employer. M/F/D/V.  This is a security-sensitive position and thereby subject to Texas Education Code §51.215. A background check will be required for the final candidate.


    CENTER FOR DIABETES AND OBESITY RESEARCH

    A post-doctoral position is available in the laboratory of Dr. Vihang Narkar at UT Institute of Molecular Medicine.  The successful candidate will use a combination of molecular biology, tissue culture, immuno-histochemistry and mouse genetic engineering to study nuclear receptor signaling in skeletal muscle diseases such as diabetes and muscular dystrophy.  This position requires a recent Ph.D. in biological sciences.  The candidate should be highly motivated and innovative, have expertise in molecular biology, cell culture and in rodent physiology, and should have published first-author paper(s) in peer-reviewed journals. 

    Interested candidates should email CV and a list of three references to:
    (No phone calls please)

    Vihang A. Narkar, Ph.D.
    Assistant Professor
    Center for Diabetes and Obesity Research
    Institute of Molecular Medicine
    University of Texas Health Science Center
    Email: vihang.a.narkar@uth.tmc.edu
    Website: http://www.uthouston.edu/imm/profile.htm?id=1402137

    The University of Texas is an EO/AA employer. M/F/D/V.  This is a security-sensitive position and thereby subject to Texas Education Code §51.215. A background check will be required for the final candidate.


    TEXAS THERAPEUTIC INSTITUTE, IMM

    Post-doctoral positions are available in the laboratory of Dr. Qingyun (Jim) Liu at the Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases. 

    The successful candidates will study the roles of G protein-coupled receptors in tumor initiation, growth, and metastasis to identify and validate potential drug targets for the development of novel treatments for cancer, or will study aromatic amino acid hydroxylases for the discovery of innovative treatments for certain genetic disorders.  The positions require a recent Ph.D. in biological sciences.  The candidates must be highly motivated and innovative, have expertise in molecular biology, cell culture and biochemistry with first author publication(s) in leading journals.

    Interested candidates should email CV to:
    Email: qingyun.liu@uth.tmc.edu

    Qingyun (Jim) Liu, Ph.D.
    Professor
    The Brown Foundation Institute of Molecular Medicine
    for the Preventation of Human Diseases
    at  The University of Texas Health Science Center at Houston
    TEXAS THERAPEUTICS INSTITUTE, IMM
    1825 Pressler Street
    Houston, TX 77030

    The University of Texas is an EO/AA employer. M/F/D/V.  This is a security-sensitive position and thereby subject to Texas Education Code §51.215. A background check will be required for the final candidate.


    If you encounter errors on this page, please contact Monica J. Bennett at 713.500.3488

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